Developed more than fifty years ago to block the release of histamines from cells, these drugs are widely available in both prescription and over-the-counter forms. They work by counteracting the body’s reaction to allergens, the ordinarily harmless substances which trigger the immune system to produce antibodies to destroy them. When you’re prone to allergies, a special type of antibody, called IgE, is produced, making you super-sensitive to the allergen. Each time you’re exposed to the offending substance, it combines with the IgE antibodies, releasing histamines that bring on sneezing, watery eyes, and runny noses.
Antihistamines, which dry mucous membranes, can also be responsible for ED as well as a drop in libido. I have had success with patients who switched from antihistamines to Nasalcrom or Flonase nasal spray. These medicines control allergic symptoms without affecting sexual function.
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